In November, 1966 Margherita Stein (alias Christian Stein) opens the first headquarters of Christian Stein Gallery in Turin, in via Teofilo Rossi 3.

From its foundation the Galley presents itself as a meeting place, hosting exhibitions and conferences. The opening exhibition was dedicated to Aldo Mondino, following Mario Schifano’s astonishing one, then in January 1967 the gallery hold the first solo show of  Alighiero Boetti. Later that year, the group show Con temp l’azione was concurrently organized with Turin-based galleries Il Punto and Sperone. Among the others, the gallery presents exhibitions of Giulio Paolini, Ettore Colla, Michelangelo Pistoletto, Giuseppe Uncini. During this first stage of activity, shows were dedicated to international artists such as Erick Dietmann, Robert Watts. The gallery also held the first Italian solo exhibitions of Robert Indiana and Gary Kuehn. In 1972, after hosting over fifty exhibitions, Galleria Christian Stein moves to a larger space in Piazza San Carlo 206, Turin.